The joystick functions in our classic grip mice can be disabled temporarily within Device Manager. Which can be accessed via control panel, or by right clicking the Start Menu.

Within device manager expand the "Human Interface Devices" section, then find the "HID-compliant game controller". Right click it and select "Disable Device". This will prevent any of your games from recognizing the Z as a joystick until you re-enable this device in Device Manager.

Alternately if you are not on Windows and using a Z1/2, Creator or Tracer, you can disable the joystick output by unplugging your mouse then holding down the "Top Thumb Button" and "Left Trigger Push" while you plug it back in. Just note that this will also prevent the X1 Control Panel from detecting your mouse until it is unplugged and reconnected.