Firstly ensure you are holding the mouse correctly.  Next, practice clicking the left-click and right-click buttons on top of the mouse.  The scroll wheel can be used like a traditional scroll wheel by scrolling with your index finger.

GT works in two modes: Point and click mode where you use it as a traditional mouse and Touch gesture mode accessed by tilting the mouse over slightly to use the stylus underneath. It allows the user a natural swipe or flick action with finger, wrist and forearm movement.

To gesture, tilt the mouse to engage the stylus, then drag the stylus on the mousing surface. To perform edge gestures, hold the rear (right-click) button and engage the stylus. Drag right to left to bring up Charms. Drag left to right to bring up application switcher. Lift stylus to launch an application. Drag up or down to zoom depending on the application being used.