By default presentation mode uses Windows keyboard shortcuts. So if you have not connected your mouse to the Swiftpoint Control Panel for Mac its shortcuts will not be recognized by the Mac version of PowerPoint.

Simply installing and running the Control Panel on your mac will put your mouse into Mac mode. But it will also allow you to switch your ProPoint into Mac (or Windows) mode on the firmware level, so that it will continue to use the appropriate shortcut keys even when the Control Panel is not available.

Even with the Control Panel not all of presentation modes functionality will work in other presentation apps like Keynote by default. As they use different shortcuts than PowerPoint for some functions. In cases like this you can use the Control Panel to modify your Presenter mode functions to match your chosen presentation software.