If you are connecting via the USB receiver and the firmware on your mouse is out of date the settings in the Control Panel may not be able to correctly apply to your mouse.
Pairing over Bluetooth will avoid this issue. But to resolve the problem completely so you can use the USB receiver with the Control Panel you will also need to complete a firmware update.
If you haven't paired over Bluetooth before, you can find pairing instructions and a demonstration video in the article below.
Once you have successfully paired over Bluetooth the firmware upgrade button will appear at the bottom right corner of the Control Panel Window.